Apparatus
- ID-nummer
- 2017.017.001
- Titel
- Apparatus
- Objektkategori
- Vetenskapliga instrument, material & modeller
- Publik beskrivning
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This apparatus was used by Jacques Dubochet in the 1980s in experiments to create images of biological molecules.
With the electron microscope, it is possible to create images of objects as small as molecules. One problem with biological molecules, however, is that they dry out and are destroyed in the vacuum needed in the electron microscope. Ice crystals also distort the image. To avoid this, Dubochet designed this apparatus, which freezes water so quickly that ice crystals do not have time to form. The samples were lowered into a cold liquid using an arm with a pair of tweezers. At first, liquid nitrogen was used, but this was later replaced by liquid ethane.
Jacques Dubochet donated the apparatus to the Nobel Prize Museum in 2017. - Pristagare
- Jacques Dubochet
Part of Apparatus